WE LOVE WHAT WE DO!
Etienne Caron, PhD
PRINCIPAL INVESTIGATOR | ASSISTANT PROFESSOR
Etienne Caron was recruited at the CHU Sainte-Justine Research Center at the Université de Montréal in September 2018 to develop an innovative research program in mass spectrometry and cancer immunotherapy. Etienne did is PhD training in the group of Prof Claude Perreault at the Université de Montreal and his postdoc at ETH-Zürich in the laboratory of Prof Ruedi Aebersold, a pioneer and world-leader in the field of proteomics and mass spectrometry. During his postdoctoral training, he has contributed to the development of the SWATH/DIA technology to advance the field of immunopeptidomics and immunotherapy. Etienne also became a world-leader in the field, founding and chairing the Human Immuno-Peptidome Project, an international initiative reuniting top leaders in mass spectrometry and immunology. His PhD and postdoctoral training has led to the publication of 23 papers in high-impact journal including Immunity, eLife, Cell Rep and Nature.
Isabelle Sirois, PhD
RESEARCH ASSOCIATE | LAB MANAGER
Following Biochemistry and COOP studies at the University of Ottawa, Isabelle completed a PhD with Drs Marie-Josée Hébert et Alexey Pshezhetsky at the Université de Montréal from 2004 to 2011. During her PhD, she characterized the secretome of apoptotic/autophagic cells using mass spectrometry and described unconventional modes of secretion relevant to chronic allograft rejection. These findings were published in significant journals including Cell Death and Differentiation and Autophagy. Isabelle completed a postdoc training with Dr Mark Basik lab and his team at McGill University. Later, she joined the team as a Research Associate. Her work described novel molecular vulnerabilities in chemoresistant TNBC tumors. Isabelle is now a Research Associate and Lab Manager at CARONLAB since Novembre 2018.
Paul Drogaris, PhD
DIRECTOR OF MASS SPECTROMETRY PLATFORM
Paul Drogaris was recruited at the CHU Sainte-Justine Research Center in January 2019 to implement a current generation mass spectrometry instrumental platform. After spending a decade in the pharma and biotech sectors from 1995 to 2005, Paul returned to academia at the Université de Montreal to complete a Ph.D. degree in the laboratory of Professor Pierre Thibault, a pioneer in the field of protein and peptide mass spectrometry. During this doctoral training period, Paul developed and implemented quantitative LC-MS approaches in support of epigenetics research, deciphering complex histone modification patterns in different organisms and disease states. This work lead to several collaborations and high-impact journal publications, including Nature Medicine and Cell. From 2012 to 2017, as group leader and laboratory head of Thrasos therapeutics, Paul established quantitative workflows for therapeutic peptide drug discovery and development for acute kidney injury and chronic kidney disease. As of January 2019, Paul is the director of the multi-omics platform at the CHU Sainte-Justine Research Center and co-member of the Caron Lab.