MISSION
MISSION
MISSION
MISSION
PUBLICATIONS
READ ABOUT OUR DISCOVERIES
Cell Systems February 16, 2022; PMID: 34637888
The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner
Hamelin DJ, Fournelle D, Grenier JC, Schockaert J, Kovalchik KA, Kubiniok P, Mostefai F, Duquette JD, Saab F, Sirois I, Smith MA, Pattijn S, Soudeyns H, Decaluwe H, Hussin J, Caron E
iScience January 18, 2022; PMID: 35141507
Understanding the constitutive presentation of MHC class I immunopeptidomes in primary tissues.
Kubiniok P, Marcu A, Bichmann L, Kuchenbecker L, Schuster H, Hamelin DJ, Duquette JD, Kovalchik KA, Wessling L, Kohlbacher O, Rammensee HG, Neidert MC, Sirois I, Caron E
STAR Protocols October 21, 2021; PMID: 34746858
RHybridFinder: An R package to process immunopeptidomic data for putative hybrid peptide discovery
Saab F, Hamelin DJ, Ma Q, Kovalchik KA, Sirois I, Faridi P, Li C, Purcell AW, Kubiniok P, Caron E
Molecular & Cellular Proteomics November 17, 2021; PMID: 34798331
MhcVizPipe: A Quality Control Software for Rapid Assessment of Small- to Large-Scale Immunopeptidome Datasets
Kovalchik K, Ma Q, Wessling L, Saab F, Duquette JD, Kubiniok P, Hamelin DJ, Faridi P, Li C, Purcell AW, Jang A, Paramithiotis E, Tognetti M, Reiter L, Bruderer R, Lanoix J, Bonneil E, Courcelles M, Thibault P, Caron E, Sirois I
J. Vis. Exp. October 15, 2021; PMID: 34723952
Immunopeptidomics: Isolation of Mouse and Human MHC Class I- and II-Associated Peptides for Mass Spectrometry Analysis
Sirois I, Isabelle M, Duquette JD, Saab F, Caron E
Molecular & Cellular Proteomics January 01, 2020
The Human Immunopeptidome Project: a roadmap to predict and treat immune diseases
Vizcaíno JA, Kuniok P, Kovalchik K, Ma Q, Despault J, Mongrain I, Deutsch EW, Peters B, Sette A, Sirois I and Caron E
Sci Data 2018, 5:180157
A tissue-based draft map of the murine
MHC class I immunopeptidome
Schuster H, Shao W, Weiss T, Pedrioli P, Roth P, Weller M, Campbell DS, Deutsch EW, Moritz RL, Rammensee HG, Aebersold R*, Caron E*
*Co-corresponding author
Nucleic Acids Research - 2018, 46 (D1):D1237-D1247
The SysteMHC Atlas project
Shao W, Pedrioli P, Wolski W, Scurtescu C, Schmid E, Vizcaino JA, Courcelles M, Schuster H, Kowalewski D, Marino F, Arlehamn CSL, Vaughan K, Peters B, Sette A, Ottenhoff THM, Meijgaarden KE, Nieuwenhuizen N, Kaufmann SHE, Schlapbach R, Castle JC, Nesvizhskii AI, Nielsen M, Deutsch EW, Campbell DS, Moritz RL, Zubarev RA, Ytterberg AJ, Purcell AW, Marcilla M, Paradela A, Wang Q, Costello CE, Ternette N, van Veelen PA, van Els CACM, Heck AJR, de Souza GA, Sollid LM, Admon A, Stevanovic S, Rammensee HG, Thibault P, Perreault C, Bassani-Sternberg M, Aebersold R*, and Caron E*
*Co-corresponding author
Immunity - 2017, 47:203-208.
A Case for a Human Immuno-Peptidome Project Consortium
Caron E§*, Aebersold R, Banaei-Esfahani A, Chong C, Bassani-Sternberg M*
§Lead contact,*Co-corresponding author
Cell Reports - 28 March 2017, 18(13):3219-3226
Precise temporal profiling of protein signaling complexes in primary cells using SWATH mass spectrometry
Caron E*, Roncagalli R*, Takeshi H, Wolski WE, Meena C, Menoita MG, Durand S, Garcia-Blesa A, Fierro-Monti I, Sajic T, Heusel M, Weiss T, Malissen M, Schlapbach R, Collins B, Ghosh S, Kitano H, Aebersold R, Malissen B, Gstaiger M.
*Co-first author
Mol Cell Proteomics - December 2015, 14(12):3105-17
Analysis of Major Histocompatibility Complex (MHC) Immunopeptidomes Using Mass Spectrometry
Caron E, Kowalewski DJ, Chiek Koh C, Sturm T, Schuster H, Aebersold R
eLife - 2015, 4:e07661
An open-source computational and data resource to analyze quantitative digital maps of immunopeptidomes
Caron E*, Espona L, Kowalewski D, Schuster H, Ternette N, Alpízar A, Schittenhelm RB, Lindestam CSA, Koh CC, Gillet L, Rabsteyn A, Sturm T, Navarro P, Kim S, Lam H, Marcilla M, Sette A, Campbell DS, Deutsch EW, Moritz RL, Purcell AW, Rammensee HG, Stevanovic S, Aebersold R*
*Co-corresponding author
Nature - 2014, 515:577-581
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
Gubin MM, Zhang X, Schuster H, Caron E, Noguchi T, Ward JP, Ivanova Y, Hundal J, Arthur CD, Krebber WJ, Mulder GE, Vesely MD, Lam SSK, Korman AJ, Allison JP, Freeman GJ, Sharpe AH, Pearce EL, Aebersold R, Rammensee HG, Melief CJM, Mardis ER, Gillanders WE, Artyomov MN, Schreiber RD
Molecular System Biology - 2011, 7:753
The MHC class I immunopeptidome conveys to the cell surface an integrative view of cellular regulation
Caron E*, Vincent K*, Fortier MH*, Laverdure JP, Bramoullé A, Hardy MP, Voisin G, Roux PP, Lemieux S, Thibault P, Perreault C.
*Co-first author
Molecular System Biology - 2010, 6:453
A comprehensive map of the mTOR signaling network
Caron E, Ghosh S, Matsuoka Y, Ashton-Beaucage D, Therrien M, Lemieux S, Perreault C, Roux PP, Kitano H
Journal of Experimental Medicine - 2008, 205:595-610
The MHC class I peptide repertoire is molded by the transcriptome
Fortier MH*, Caron E*, Hardy MP, Voisin G, Lemieux S, Perreault C, Thibault P
*Co-first author
ASBMB Today November 11, 2021
Pondering the power of connections in the post–COVID-19 era
Caron E
Methods Mol Biol. 2022; PMID: 34905171
Generation of HLA Allele-Specific Spectral Libraries to Identify and Quantify Immunopeptidomes by SWATH/DIA-MS
Kovalchik K, Hamelin D, Caron E
Methods Mol Biol. 2020; PMID: 32124319
The SysteMHC Atlas: a Computational Pipeline, a Website, and a Data Repository for Immunopeptidomic Analyses
Shao W, Caron E, Pedrioli P, Aebersold R
